Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | PPARA | Q07869 | 3/20 | 0.36 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.36 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316148 | 1.00 | PTPN1 (0.38) | PTPN1PPARAADCY8ADCY1P2RY14 | |
| SCHEMBL5310786 | 0.92 | ADCY8 (0.39) | PTPN1ADCY8ADCY1MAPTLMNA | |
| SCHEMBL5310781 | 0.92 | ADCY8 (0.39) | PTPN1ADCY8ADCY1MAPTLMNA | |
| SCHEMBL5310760 | 0.88 | PTPN1 (0.39) | PTPN1PPARAMAPTLMNASMN1; SMN2 | |
| SCHEMBL5310753 | 0.88 | PTPN1 (0.39) | PTPN1PPARAMAPTLMNASMN1; SMN2 | |
| SCHEMBL5310820 | 0.88 | PTPN1 (0.40) | PTPN1PPARAMAPTLMNASMN1; SMN2 | |
| SCHEMBL5310815 | 0.88 | PTPN1 (0.40) | PTPN1PPARAMAPTLMNASMN1; SMN2 | |
| SCHEMBL14530962 | 0.87 | PTPN1 (0.40) | PTPN1PPARAMAPTLMNASMN1; SMN2 | |
| SCHEMBL5316162 | 0.87 | PTPN1 (0.38) | PTPN1PPARAMAPTLMNASMN1; SMN2 | |
| SCHEMBL5311834 | 0.86 | MAPT (0.47) | PTPN1PPARAMAPTSMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058504-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES, LTD. (KR) | 2007-05-24 | — | — | WO | disclosed |