Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL114536 | 0.93 | GAA (0.54) | GAATSHRTDP1RAB9AHTT | |
| SCHEMBL20497334 | 0.89 | GAA (0.50) | GAATSHRTDP1RAB9ALOXL2 | |
| SCHEMBL28802695 | 0.86 | PARP10 (0.59) | GAATSHRTDP1RAB9AMAOB | |
| SCHEMBL30034400 | 0.84 | EPHX2 (0.45) | GAATSHRTDP1RAB9ALOXL2 | |
| SCHEMBL11844391 | 0.81 | GAA (0.51) | GAATSHRTDP1RAB9AHTT | |
| SCHEMBL30736424 | 0.81 | MAOB (0.50) | GAATSHRTDP1RAB9AHTT | |
| Hydrochloric Acid SCHEMBL11844386 | 0.80 | GAA (0.50) | GAATSHRTDP1RAB9AHTT | |
| SCHEMBL30437401 | 0.78 | KMT2A (0.50) | TDP1IDO1L3MBTL1PARP10SMN1; SMN2 | |
| SCHEMBL29034684 | 0.78 | MAPK8 (0.45) | GAATSHRTDP1RAB9AHTT | |
| SCHEMBL6646091 | 0.77 | MAOB (0.59) | GAATSHRTDP1RAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160280732-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-09-29 | — | — | US | disclosed |
| EP-3056487-A1 | SYNTHESIS OF ENONE INTERMEDIATE | President and Fellows of Harvard College (US) | 2016-08-17 | — | — | EP | disclosed |
| EP-2487160-A1 | Synthesis of Enone Intermediate | President and Fellows of Harvard College (US) | 2012-08-15 | — | — | EP | disclosed |
| WO-2007008226-A2 | PALLADIUM-CATALYZED CARBON-CARBON BOND FORMING REACTIONS | THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160280732-A1 | MOENOMYCIN ANALOGS, METHODS OF SYNTHESIS, AND USES THEREOF | RDX, RPS4X, MLX | GAA 712/4885TSHR 1099/4885TDP1 3442/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.