Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 9/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267634 | 0.92 | NR1H2 (0.40) | F2RL3NR1H2NR1H3RORCGRM2 | |
| SCHEMBL5320785 | 0.91 | F2RL3 (0.43) | F2RL3CYP2C9CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL5272346 | 0.90 | NR1H2 (0.39) | F2RL3NR1H2NR1H3RORCGRM2 | |
| SCHEMBL5317487 | 0.89 | F2RL3 (0.52) | F2RL3RORCCYP2C9CYP2D6AKR1B1 | |
| SCHEMBL5373644 | 0.89 | NR1H2 (0.38) | F2RL3NR1H2NR1H3RORCGRM2 | |
| SCHEMBL5273572 | 0.89 | F2RL3 (0.40) | F2RL3CYP2C9CYP2D6CYP1A2CYP3A4 | |
| SCHEMBL5383568 | 0.88 | NR1H2 (0.38) | F2RL3NR1H2NR1H3RORCGRM2 | |
| SCHEMBL5319989 | 0.88 | AKR1B1 (0.52) | RORCCYP2C9AKR1B1CYP1A2PTGDR2 | |
| SCHEMBL5316549 | 0.86 | SLC22A12 (0.42) | RORCCYP2C9AKR1B1ALOX5APPPARG | |
| SCHEMBL5323485 | 0.86 | FFAR4 (0.42) | RORCCYP2C9AKR1B1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | claimed |