Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 10/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | PPM1A | P35813 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323273 | 0.92 | F2RL3 (0.46) | F2RL3KCNK3AKR1B1RORCPPM1A | |
| SCHEMBL5316861 | 0.90 | F2RL3 (0.45) | F2RL3KCNK3AKR1B1RORCPPM1A | |
| SCHEMBL5321104 | 0.89 | F2RL3 (0.45) | F2RL3CYP2C9CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5316306 | 0.89 | F2RL3 (0.42) | F2RL3AKR1B1RORCCYP2C9CYP1A2 | |
| SCHEMBL5342237 | 0.89 | F2RL3 (0.44) | F2RL3KCNK3AKR1B1RORCPPM1A | |
| SCHEMBL5346581 | 0.88 | F2RL3 (0.43) | F2RL3KCNK3AKR1B1RORCPPM1A | |
| SCHEMBL5323079 | 0.86 | AKR1B1 (0.43) | F2RL3KCNK3AKR1B1RORCCYP2C9 | |
| SCHEMBL5317096 | 0.85 | AKR1B1 (0.43) | F2RL3KCNK3AKR1B1RORCCYP2C9 | |
| SCHEMBL27956755 | 0.83 | KCNK3 (0.41) | F2RL3KCNK3AKR1B1RORCCYP2C9 | |
| SCHEMBL5321176 | 0.83 | F2RL3 (0.45) | F2RL3KCNK3RORCPPM1ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | claimed |