Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531640 | 1.00 | CETP (0.51) | CETPNR1I2 | |
| SCHEMBL5178599 | 1.00 | CETP (0.51) | CETPNR1I2 | |
| SCHEMBL531781 | 1.00 | CETP (0.51) | CETPNR1I2 | |
| SCHEMBL5178774 | 0.88 | CETP (0.51) | CETPNR1I2 | |
| SCHEMBL5240943 | 0.88 | CETP (0.51) | CETPNR1I2 | |
| SCHEMBL17998199 | 0.88 | CETP (0.51) | CETPNR1I2 | |
| SCHEMBL531341 | 0.88 | CETP (0.51) | CETPNR1I2 | |
| SCHEMBL531911 | 0.88 | CETP (0.61) | CETPNR1I2 | |
| SCHEMBL531912 | 0.88 | CETP (0.61) | CETPNR1I2 | |
| SCHEMBL532579 | 0.88 | CETP (0.61) | CETPNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415759-A1 | CETP inhibitors | Merck Sharp & Dohme Corporation (US) | 2012-02-08 | — | — | EP | disclosed |
| EP-1765793-A1 | CETP INHIBITORS | Merck and Co., Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006014413-A1 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2006-02-09 | — | — | WO | disclosed |