Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | INSR | P06213 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL5316431 | 0.88 | KDM4E (0.41) | KDM4EALDH1A1HTTLMNAGAA | |
| SCHEMBL4876085 | 0.77 | HTT (0.41) | KDM4EALDH1A1HTTLMNAGAA | |
| SCHEMBL4883332 | 0.72 | HTT (0.39) | KDM4EALDH1A1HTTLMNAGAA | |
| Perchlorate SCHEMBL4876077 | 0.66 | KDM4E (0.44) | KDM4EALDH1A1HTTLMNAGAA | |
| Perchlorate SCHEMBL4876095 | 0.66 | KDM4E (0.44) | KDM4EALDH1A1HTTLMNAGAA | |
| Perchlorate SCHEMBL4883333 | 0.64 | ALDH1A1 (0.42) | KDM4EALDH1A1HTTLMNAGAA | |
| Iodide SCHEMBL17187192 | 0.60 | KDM4E (0.65) | KDM4EALDH1A1HTTLMNAGAA | |
| Bromide SCHEMBL29389671 | 0.60 | KDM4E (0.61) | KDM4EALDH1A1HTTLMNAGAA | |
| SCHEMBL3363229 | 0.58 | MEN1 (0.83) | KDM4EALDH1A1HTTLMNAGAA | |
| SCHEMBL9064445 | 0.58 | MEN1 (0.83) | KDM4EALDH1A1HTTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841428-A1 | NOVEL QUINOLINIUM SALTS AND DERIVATIVES | Immusol Incorporated (US) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006078754-A1 | NOVEL QUINOLINIUM SALTS AND DERIVATIVES | IMMUSOL INCORPORATED (US) | 2006-07-27 | — | — | WO | disclosed |