Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17275467 | 0.82 | TSHR (0.45) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL22370929 | 0.82 | MEN1 (0.56) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL27171240 | 0.82 | MEN1 (0.56) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL347257 | 0.82 | MEN1 (0.56) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL28623788 | 0.82 | TSHR (0.45) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL15670960 | 0.82 | KMT2A (0.59) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL15670729 | 0.82 | KMT2A (0.59) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL14908817 | 0.77 | MEN1 (0.50) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL15670940 | 0.77 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL15812399 | 0.77 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2415759-A1 | CETP inhibitors | Merck Sharp & Dohme Corporation (US) | 2012-02-08 | — | — | EP | disclosed |