SCHEMBL5316655

SCHEMBL5316655

CCC(C)c1ccc2[nH]nnc2c1-c1cc(C(C)(C)CC)cc(C(C)(C)C)c1O

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
RORC P51449 1/20 0.33
HSP90AA1 P07900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28694451 0.81 NPC1 (0.31)
SCHEMBL29733682 0.79
SCHEMBL5477964 0.79
SCHEMBL28557438 0.76 RORC (0.32) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL30367475 0.75 HSP90AA1 (0.43) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL28576876 0.74 RORC (0.33) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL3268199 0.73 NPC1 (0.34)
SCHEMBL29367588 0.73 NPC1 (0.34)
SCHEMBL30375701 0.73 NPC1 (0.34)
SCHEMBL2356488 0.73 HSP90AA1 (0.41) CYP1A2CYP3A4CYP2C9TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007056556-A2 POLYETHYLENE GLYCOL CONJUGATES OF PYRIDINIUM AND THIAZOLIUM COMPOUNDS AND METHODS OF USING THE SAME MYCOSOL, INC. (US) 2007-05-18 WO disclosed