SCHEMBL5316686 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	NTRK1	P04629	1/20	0.42

▸	NTRK2	Q16620	1/20	0.42

▸	PLK1	P53350	1/20	0.38

▸	PPARA	Q07869	4/20	0.35

▸	PPARG	P37231	2/20	0.35

▸	MTTP	P55157	4/20	0.35

▸	NR1H4	Q96RI1	2/20	0.33

▸	PPARD	Q03181	1/20	0.33

▸	HSPH1	Q92598	1/20	0.33

▸	SORT1	Q99523	4/20	0.33

▸	MCHR1	Q99705	1/20	0.33

▸	PTGFR	P43088	1/20	0.33

▸	KCNH2	Q12809	1/20	0.32

▸	PTGDR2	Q9Y5Y4	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5318139	0.95	NTRK1 (0.40)	NTRK1NTRK2PLK1PPARAPPARG
SCHEMBL5318808	0.95	NTRK1 (0.39)	NTRK1NTRK2PLK1PPARAPPARG
SCHEMBL403346	0.94	NTRK1 (0.42)	NTRK1NTRK2PLK1PPARAPPARG
SCHEMBL5316647	0.93	NTRK1 (0.41)	NTRK1NTRK2PLK1PPARAPPARG
SCHEMBL10205609	0.93	NTRK1 (0.42)	NTRK1NTRK2PLK1PPARAPPARG
SCHEMBL402751	0.92	NTRK1 (0.40)	NTRK1NTRK2PLK1PPARAPPARG
SCHEMBL5318000	0.91	NTRK1 (0.43)	NTRK1NTRK2PLK1PPARAPPARG
SCHEMBL402750	0.91	NTRK1 (0.40)	NTRK1NTRK2PLK1PPARAPPARG
SCHEMBL400959	0.91	NTRK1 (0.40)	NTRK1NTRK2PLK1PPARAPPARG
SCHEMBL5317957	0.90	NTRK1 (0.39)	NTRK1NTRK2PLK1PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1803452-A1	ESTER DERIVATIVE AND PHARMACEUTICAL USE THEREOF	Japan Tobacco, Inc. (JP)	2007-07-04	—	—	EP	claimed