Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.47 |
| ▸ | CA2 | P00918 | 5/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8333388 | 0.84 | MAPT (0.53) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL1018068 | 0.81 | MAPT (0.50) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL2098230 | 0.81 | CYP19A1 (0.50) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL10409572 | 0.81 | MAPT (0.50) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL1014212 | 0.81 | CA2 (0.58) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL1018066 | 0.78 | MAPT (0.47) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL1020576 | 0.78 | CA2 (0.61) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL506270 | 0.78 | MAPT (0.55) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL29297466 | 0.77 | MAPT (0.46) | MAPTCA1CA2CA9CA12 | |
| SCHEMBL13423489 | 0.76 | MAPT (0.53) | MAPTCA1CA2CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069986-A1 | NEW OXABISPIDINE COMPOUNDS FOR THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2007-06-21 | — | — | WO | disclosed |