Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 19/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5316616 | 0.83 | MCHR1 (0.59) | MCHR1KCNH2 | |
| Hydrochloric Acid SCHEMBL4923401 | 0.82 | MCHR1 (0.58) | MCHR1KCNH2 | |
| SCHEMBL979665 | 0.80 | KDM4E (0.71) | — | |
| SCHEMBL5316462 | 0.79 | MCHR1 (0.65) | MCHR1KCNH2 | |
| SCHEMBL5322252 | 0.77 | DRD4 (0.60) | MCHR1KCNH2DRD4 | |
| Hydrochloric Acid SCHEMBL27710070 | 0.77 | MCHR1 (0.63) | MCHR1KCNH2 | |
| SCHEMBL5316946 | 0.77 | MCHR1 (0.72) | MCHR1KCNH2 | |
| SCHEMBL4919276 | 0.76 | MCHR1 (0.57) | MCHR1KCNH2 | |
| Chlorolithium SCHEMBL4922637 | 0.76 | MCHR1 (0.62) | MCHR1KCNH2 | |
| Chlorolithium SCHEMBL4927349 | 0.75 | MCHR1 (0.68) | MCHR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831194-A1 | HETEROCYCLIC MCHr1 ANTAGONISTS AND THEIR USE IN THERAPY | AstraZeneca AB (SE) | 2007-09-12 | — | — | EP | claimed |
| WO-2006068594-A1 | HETEROCYCLIC MCHr1 ANTAGONISTS AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | claimed |
| CN-101124216-A | Heterocyclic MCHr1 antagonists and their use in therapy | ASTRAZENECA AB (SE) | 2008-02-13 | — | — | CN | disclosed |
| EP-1831194-A1 | HETEROCYCLIC MCHr1 ANTAGONISTS AND THEIR USE IN THERAPY | AstraZeneca AB (SE) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006068594-A1 | HETEROCYCLIC MCHr1 ANTAGONISTS AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |