Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4923401 | 0.99 | MCHR1 (0.58) | MCHR1KCNH2 | |
| Hydrochloric Acid SCHEMBL5318750 | 0.87 | MCHR1 (0.66) | MCHR1KCNH2 | |
| SCHEMBL5316462 | 0.83 | MCHR1 (0.65) | MCHR1KCNH2 | |
| SCHEMBL5316753 | 0.83 | MCHR1 (0.53) | MCHR1KCNH2 | |
| SCHEMBL27690410 | 0.82 | MCHR1 (0.59) | MCHR1KCNH2 | |
| SCHEMBL8109237 | 0.82 | KDM4E (0.65) | KCNH2 | |
| SCHEMBL6941820 | 0.82 | KDM4E (0.65) | KCNH2 | |
| SCHEMBL5322252 | 0.81 | DRD4 (0.60) | MCHR1KCNH2 | |
| SCHEMBL5316946 | 0.81 | MCHR1 (0.72) | MCHR1KCNH2 | |
| Hydrochloric Acid SCHEMBL27710070 | 0.81 | MCHR1 (0.63) | MCHR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831194-A1 | HETEROCYCLIC MCHr1 ANTAGONISTS AND THEIR USE IN THERAPY | AstraZeneca AB (SE) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006068594-A1 | HETEROCYCLIC MCHr1 ANTAGONISTS AND THEIR USE IN THERAPY | ASTRAZENECA AB (SE) | 2006-06-29 | — | — | WO | disclosed |