Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.64 |
| ▸ | NR3C2 | P08235 | 18/20 | 0.64 |
| ▸ | PGR | P06401 | 13/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4065663 | 0.83 | NR3C1 (0.72) | NR3C1NR3C2PGR | |
| SCHEMBL4068700 | 0.79 | NR3C1 (0.60) | NR3C1NR3C2PGR | |
| SCHEMBL4073757 | 0.79 | NR3C1 (0.71) | NR3C1NR3C2PGR | |
| SCHEMBL4066146 | 0.78 | NR3C2 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL4065868 | 0.77 | NR3C1 (0.78) | NR3C1NR3C2PGR | |
| SCHEMBL4069224 | 0.77 | NR3C1 (0.74) | NR3C1NR3C2PGR | |
| SCHEMBL4069499 | 0.77 | NR3C1 (0.74) | NR3C1NR3C2PGR | |
| SCHEMBL4071393 | 0.76 | NR3C1 (0.75) | NR3C1NR3C2PGR | |
| SCHEMBL4067589 | 0.75 | NR3C2 (0.71) | NR3C1NR3C2PGR | |
| SCHEMBL4408081 | 0.75 | NR3C1 (0.68) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836166-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006071609-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-07-06 | — | — | WO | disclosed |