Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 8/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317018 | 1.00 | SLC6A2 (0.44) | SLC6A2SLC6A4SLC6A3CYP2D6REN | |
| SCHEMBL9996421 | 0.91 | REN (0.43) | SLC6A2SLC6A4SLC6A3CYP2D6REN | |
| SCHEMBL9996424 | 0.91 | REN (0.43) | SLC6A2SLC6A4SLC6A3CYP2D6REN | |
| SCHEMBL3615389 | 0.91 | REN (0.43) | SLC6A2SLC6A4SLC6A3CYP2D6REN | |
| SCHEMBL9996423 | 0.91 | REN (0.43) | SLC6A2SLC6A4SLC6A3CYP2D6REN | |
| SCHEMBL3607345 | 0.87 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2D6REN | |
| SCHEMBL3618328 | 0.87 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2D6REN | |
| SCHEMBL3618327 | 0.87 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2D6REN | |
| SCHEMBL3618332 | 0.87 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2D6REN | |
| SCHEMBL3612610 | 0.87 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2D6REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117557-A2 | DIAMINOPROPANOL RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |