Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 19/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4499790 | 0.88 | P2RY12 (0.47) | P2RY12 | |
| SCHEMBL4109436 | 0.81 | P2RY12 (0.53) | P2RY12 | |
| SCHEMBL4098095 | 0.79 | P2RY12 (0.61) | P2RY12MEN1KMT2A | |
| SCHEMBL2420272 | 0.73 | NR1H2 (0.51) | P2RY12MEN1KMT2A | |
| SCHEMBL5592419 | 0.73 | SMN1; SMN2 (0.47) | P2RY12MEN1KMT2A | |
| SCHEMBL4105686 | 0.72 | P2RY12 (0.58) | P2RY12MEN1KMT2A | |
| SCHEMBL5592423 | 0.72 | P2RY12 (0.52) | P2RY12MEN1KMT2A | |
| SCHEMBL4500021 | 0.71 | CXCR3 (0.43) | P2RY12 | |
| SCHEMBL4518854 | 0.70 | CXCR3 (0.44) | P2RY12 | |
| SCHEMBL24215438 | 0.70 | SMN1; SMN2 (0.45) | P2RY12MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836189-A1 | NOVEL PYRIDINE COMPOUNDS | AstraZeneca AB (SE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006073361-A1 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2006-07-13 | — | — | WO | disclosed |