SCHEMBL5317211

SCHEMBL5317211

C=C(O)CCCCCCCCCCCCCCC

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.55
PPARG P37231 7/20 0.55
PPARD Q03181 7/20 0.55
PPARA Q07869 7/20 0.55
HDAC11 Q96DB2 5/20 0.55
TSHR P16473 5/20 0.55
PTPN1 P18031 3/20 0.55
ALDH1A1 P00352 2/20 0.55
TLR2 O60603 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
FABP4 P15090 2/20 0.55
KMT2A Q03164 2/20 0.55
SLC22A6 Q4U2R8 1/20 0.55
SLC22A8 Q8TCC7 1/20 0.55
MEN1 O00255 1/20 0.55
ESR1 P03372 1/20 0.55
ALOX15 P16050 1/20 0.55
PDE4A P27815 1/20 0.55
PDE3A Q14432 1/20 0.55
HSD17B10 Q99714 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2514471 1.00 GPR84 (0.55) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL4558847 1.00 GPR84 (0.55) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL805230 1.00 GPR84 (0.55) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL7719583 1.00 GPR84 (0.55) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL19382202 1.00 GPR84 (0.55) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL18823640 1.00 GPR84 (0.55) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL49642 1.00
SCHEMBL2745492 1.00 GPR84 (0.55) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL18619738 1.00 GPR84 (0.55) GPR84PPARGPPARDPPARAHDAC11
SCHEMBL1905995 1.00 GPR84 (0.55) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007079563-A1 COMPOSITION OF CHEMICALS FOR MANIPULATING THE BEHAVIOUR OF THE PISTACHIO TWIG BORER, KERMANIA PISTACIELLA (LEPIDOPTERA: OINOPHILIDAE) GRIES REGINE (CA) 2007-07-19 WO claimed
US-20120128796-A1 Extracts and Compounds from Ficus Benghalensis for Increasing Hair Growth and Decreasing Hair Loss ALVI ARMANI GENOMICS INC. 2012-05-24 US disclosed
US-20120035119-A1 Extracts and Compounds from Ficus Benghalensis for Increasing Hair Growth and Decreasing Hair Loss Alvia FZE (AE) 2012-02-09 US disclosed
US-7452679-B2 Branched peptide amphiphiles, related epitope compounds and self assembled structures thereof NORTHWESTERN UNIVERSITY (US) 2008-11-18 US disclosed
WO-2007128344-A1 DESIGN AND SYNTHESIS OF BIOTINYLATED PROBES FOR N-ACYL-ETHANOLAMINES UNIVERSITA' DEGLI STUDI DI ROMA 'TOR VERGATA' (IT) 2007-11-15 WO disclosed
WO-2007079563-A1 COMPOSITION OF CHEMICALS FOR MANIPULATING THE BEHAVIOUR OF THE PISTACHIO TWIG BORER, KERMANIA PISTACIELLA (LEPIDOPTERA: OINOPHILIDAE) GRIES REGINE (CA) 2007-07-19 WO disclosed
WO-2007079563-A1 COMPOSITION OF CHEMICALS FOR MANIPULATING THE BEHAVIOUR OF THE PISTACHIO TWIG BORER, KERMANIA PISTACIELLA (LEPIDOPTERA: OINOPHILIDAE) GRIES REGINE (CA) 2007-07-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120128796-A1 Extracts and Compounds from Ficus Benghalensis for Increasing Hair Growth and Decreasing Hair Loss CAT, SHH, TYR GPR84 3030/4885PPARG 1656/4885PPARD 1743/4885
US-20120035119-A1 Extracts and Compounds from Ficus Benghalensis for Increasing Hair Growth and Decreasing Hair Loss SHH, TYR, CAT GPR84 3075/4885PPARG 1216/4885PPARD 1361/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.