SCHEMBL5317265

SCHEMBL5317265

CCC=C(C)C(=O)OC(=O)C(C)=CCC

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
TDP1 Q9NUW8 2/20 0.38
GLO1 Q04760 1/20 0.33
LMNA P02545 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TSHR P16473 2/20 0.32
FFAR3 O14843 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
SOAT1 P35610 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10825002 1.00 ALDH1A1 (0.38) ALDH1A1TDP1GLO1LMNAHSD17B10
SCHEMBL9245453 0.97 ALDH1A1 (0.36) ALDH1A1TDP1GLO1LMNAHSD17B10
SCHEMBL7522645 0.97 ALDH1A1 (0.36) ALDH1A1TDP1GLO1LMNAHSD17B10
SCHEMBL5167976 0.93 ALDH1A1 (0.33) ALDH1A1TDP1GLO1
SCHEMBL28212797 0.91 ALDH1A1 (0.32) ALDH1A1TDP1
SCHEMBL9245461 0.91 GRIK1 (0.33) ALDH1A1TDP1FFAR3
SCHEMBL4098148 0.90 ALDH1A1 (0.41) ALDH1A1TDP1GLO1LMNAHSD17B10
SCHEMBL8360659 0.90 ALDH1A1 (0.41) ALDH1A1TDP1GLO1LMNAHSD17B10
SCHEMBL3896936 0.89 CYP2D6 (0.33) ALDH1A1TDP1CYP2D6CYP2C19
SCHEMBL3345135 0.89 ALDH1A1 (0.39) ALDH1A1TDP1HSD17B10TSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4517381-A HERBICIDES MITSUI TOATSU CHEMICALS, INC. (JP) 1985-05-14 US claimed
JP-60023357-A None JP disclosed
JP-61167653-A None JP disclosed
WO-2023199324-A1 MIXTURE OF 3-HEXENYL ESTER ISOMERS AND USES THEREOF AGAN AROMA & FINE CHEMICALS LTD. (IL) 2023-10-19 WO disclosed
EP-1745012-A2 COMPOSITIONS OF ALLOSTERIC HEMOGLOBIN MODIFIERS AND METHODS OF MAKING THE SAME Allos Therapeutics, Inc. (US) 2007-01-24 EP disclosed
WO-2005102305-A2 COMPOSITIONS OF ALLOSTERIC HEMOGLOBIN MODIFIERS AND METHODS OF MAKING THE SAME ALLOS THERAPEUTICS, INC. (US) 2005-11-03 WO disclosed
JP-S61167653-A N-(3-HALOGENO-4-ISOPROPYLPHENYL)-2-METHYL-2-PENTENAMIDE DERIVATIVE AND SELECTIVE HERBICIDE MITSUI TOATSU CHEM INC 1986-07-29 JP disclosed
US-4517381-A HERBICIDES MITSUI TOATSU CHEMICALS, INC. (JP) 1985-05-14 US disclosed
JP-S6023357-A 2-METHYL-4'-ISOPROPYL-2-PENTENOYLANILIDE AND SELECTIVE HERBICIDE MITSUI TOATSU CHEM INC 1985-02-05 JP disclosed
US-4476273-A Thermosetting compositions comprising conjugated diene polymers having pendant unsaturated groups and calcium carbonate PHILLIPS PETROLEUM COMPANY (US) 1984-10-09 US disclosed