Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 12/20 | 0.79 |
| ▸ | TAS1R1 | Q7RTX1 | 12/20 | 0.79 |
| ▸ | TAS1R2 | Q8TE23 | 12/20 | 0.79 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317303 | 1.00 | TAS1R3 (0.79) | TAS1R3TAS1R1TAS1R2RECQLALDH1A1 | |
| SCHEMBL5394823 | 0.88 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL701644 | 0.88 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2MEN1KMT2A | |
| SCHEMBL702742 | 0.85 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2RECQLALDH1A1 | |
| SCHEMBL29412432 | 0.85 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2RECQLALDH1A1 | |
| SCHEMBL702741 | 0.85 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2RECQLALDH1A1 | |
| SCHEMBL702397 | 0.84 | TAS1R3 (0.64) | TAS1R3TAS1R1TAS1R2RECQLALDH1A1 | |
| SCHEMBL20860977 | 0.84 | TAS1R3 (0.64) | TAS1R3TAS1R1TAS1R2RECQLALDH1A1 | |
| SCHEMBL5277236 | 0.84 | TAS1R3 (0.64) | TAS1R3TAS1R1TAS1R2RECQLALDH1A1 | |
| SCHEMBL702097 | 0.78 | TAS1R3 (1.00) | TAS1R3TAS1R1TAS1R2RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1848289-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | Senomyx, Inc. (US) | 2007-10-31 | — | — | EP | disclosed |
| WO-2006084246-A2 | AROMATIC AMIDES AND UREAS AND THEIR USES AS SWEET AND/OR UMAMI FLAVOR MODIFIERS, TASTANTS AND TASTE ENHANCERS | SENOMYX, INC. (US) | 2006-08-10 | — | — | WO | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |