Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1049314 | 0.92 | MEN1 (0.43) | PTGDR2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5319201 | 0.90 | CYP1A2 (0.43) | PTGDR2KDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5319424 | 0.90 | TP53 (0.47) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1049540 | 0.88 | PTGDR2 (0.42) | PTGDR2MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL1046780 | 0.87 | PPARG (0.44) | PTGDR2MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL1050802 | 0.87 | PTGER1 (0.46) | PTGDR2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL5318767 | 0.87 | PPARG (0.41) | PTGDR2KDM4ECYP1A2CYP3A4CYP2C8 | |
| SCHEMBL1050090 | 0.86 | PTGDR2 (0.41) | PTGDR2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL1050165 | 0.86 | SLC22A12 (0.44) | PTGDR2MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL1048230 | 0.86 | PTGDR2 (0.39) | PTGDR2MEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | claimed |