Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 7/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 6/20 | 0.58 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.45 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27482613 | 0.98 | CA2 (0.58) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL27669334 | 0.98 | CA2 (0.58) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL27669336 | 0.98 | CA2 (0.58) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL27688216 | 0.98 | CA2 (0.58) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL8932140 | 0.98 | CA2 (0.58) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL7650538 | 0.98 | CA2 (0.58) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL2937529 | 0.98 | CA2 (0.58) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL7654397 | 0.98 | CA2 (0.58) | CA2MAPK1CA1GRIK1GRIK2 | |
| SCHEMBL465030 | 0.92 | CA2 (0.70) | CA2MAPK1CA1SLC1A2SLC1A1 | |
| SCHEMBL14125944 | 0.90 | CA2 (0.67) | CA2MAPK1CA1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 177 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801493-B | It is used to treat the 2- Phenyl aminopyrimidine derivants of Parkinson's disease as kinases LRRK2 conditioning agents | 健泰科生物技术公司 | 2018-09-21 | — | — | CN | claimed |
| CN-104854092-B | Pyridine-2-amides useful as CB2 agonists | 霍夫曼-拉罗奇有限公司 | 2018-08-10 | — | — | CN | claimed |
| CN-103987698-B | 2-phenylaminopyrimidine derivatives as kinase LRRK2 modulators for the treatment of Parkinson's disease | HOFFMAN-LA ROCHE LTD. (CH) | 2016-04-20 | — | — | CN | claimed |
| CN-104854092-A | PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS | HOFFMANN LA ROCHE | 2015-08-19 | — | — | CN | claimed |
| CN-103987698-A | 2-Phenylaminopyrimidine derivatives as kinase LRRK2 modulators for the treatment of Parkinson's disease | HOFFMANN LA ROCHE | 2014-08-13 | — | — | CN | claimed |
| EP-1478335-B1 | PERFUME CONTAINING SURFACTANT COMPOSITIONS HAVING PERFUME BURST WHEN DILUTED AND PROCESS THEREOF | UNILEVER PLC (GB) | 2014-07-30 | — | — | EP | claimed |
| US-7348299-B2 | Cleansing bar with distributed polymeric network providing enhanced delivery | CONOPCO, INC. (US) | 2008-03-25 | — | — | US | claimed |
| US-20060281650-A1 | Cleansing bar with distributed polymeric network providing enhanced delivery | CONOPCO, INC. D/B/A UNILEVER | 2006-12-14 | — | — | US | claimed |
| US-6998382-B2 | Process for making perfume containing surfactant compositions having perfume burst and enhanced perfume deposition when diluted | UNILEVER HOME & PERSONAL CARE USA, A DIVISION OF CONOPCO, INC. (US) | 2006-02-14 | — | — | US | claimed |
| US-6858574-B2 | Process for making perfume containing surfactant compositions having perfume burst when diluted | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. (US) | 2005-02-22 | — | — | US | claimed |
| US-20030166497-A1 | Process for making perfume containing surfactant compositions having perfume burst and enhanced perfume deposition when diluted | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-09-04 | — | — | US | claimed |
| US-20030166499-A1 | Perfume containing surfactant compositions having perfume burst when diluted | UNILEVER HOME & PERSONAL CARE USA, DIVISION OF CONOPCO, INC. | 2003-09-04 | — | — | US | claimed |
| WO-2003072078-A1 | PERFUME CONTAINING SURFACTANT COMPOSITIONS HAVING PERFUME BURST WHEN DILUTED AND PROCESS THEREOF | UNILEVER PLC (GB) | 2003-09-04 | — | — | WO | claimed |
| US-4317752-A | POLYURETHANE FOAMS; INSULATION; CONSTRUCTION MATERIALS | BLOUNT DAVID H | 1982-03-02 | — | — | US | claimed |
| US-4280006-A | Process for the production of polyisocyanate silicate plastics utilizing an alkali metal cellulose silicate condensation product | BLOUNT DAVID H | 1981-07-21 | — | — | US | claimed |
| US-4262108-A | FIREPROOF CONSTRUCTION MATERIALS, INSULATION | BLOUNT DAVID H | 1981-04-14 | — | — | US | claimed |
| US-4238375-A | Process for the production of organic halosilicon acid resinous products and their reaction products utilizing phenol compounds | BLOUNT DAVID H | 1980-12-09 | — | — | US | claimed |
| US-4198491-A | Process for the production of organic halosilicon acid resinous products and their reaction products | BLOUNT DAVID H | 1980-04-15 | — | — | US | claimed |
| US-4153764-A | Process for the production of polyisocyanate organic silicate solid/cellular solid product | BLOUNT DAVID H | 1979-05-08 | — | — | US | claimed |
| US-3981831-A | REACTION OF ORGANIC POLYISOCYANATE WITH ALKALI METAL SILICATE OR SILICA SOL | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-21 | — | — | US | claimed |