Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 16/20 | 0.76 |
| ▸ | TLR8 | Q9NR97 | 13/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3970054 | 0.88 | TLR7 (0.78) | TLR7TLR8TDP1 | |
| Cpg-52852 SCHEMBL29371102 | 0.87 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL728302 | 0.87 | TLR7 (0.75) | TLR7TLR8TDP1 | |
| Cpg-52852 SCHEMBL483385 | 0.87 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL2744306 | 0.86 | TLR7 (0.83) | TLR7TLR8 | |
| SCHEMBL3927223 | 0.85 | TLR7 (0.73) | TLR7TLR8 | |
| SCHEMBL29852269 | 0.85 | TLR7 (0.85) | TLR7TLR8 | |
| SCHEMBL483689 | 0.85 | TLR7 (0.85) | TLR7TLR8 | |
| SCHEMBL15104225 | 0.84 | TLR7 (0.71) | TLR7TLR8 | |
| SCHEMBL728467 | 0.84 | TLR7 (0.84) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1851224-A2 | HYDROXYALKYL SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006098852-A2 | HYDROXYALKYL SUBSTITUTED IMIDAZOQUINOLINES | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2006-09-21 | — | — | WO | disclosed |