Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 4/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.50 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27533460 | 1.00 | TSHR (0.57) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL29285270 | 0.97 | TSHR (0.57) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL130709 | 0.97 | TSHR (0.57) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL5317593 | 0.97 | TSHR (0.57) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL28450761 | 0.97 | TSHR (0.57) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL25393746 | 0.97 | TSHR (0.57) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL29062899 | 0.97 | TSHR (0.57) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL10006039 | 0.94 | TSHR (0.56) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL9436087 | 0.92 | TSHR (0.60) | TSHRALDH1A1LMNAMAPK1TP53 | |
| SCHEMBL2584734 | 0.92 | SERPINE1 (0.55) | TSHRALDH1A1LMNAMAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636310-A1 | ACRYLIC DISPERSING AGENTS IN NANOCOMPOSITES | Polymers Australia PTY Limited (AU) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004113436-A1 | ACRYLIC DISPERSING AGENTS IN NANOCOMPOSITES | POLYMERS AUSTRALIA PTY. LIMITED (AU) | 2004-12-29 | — | — | WO | disclosed |