Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.67 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.65 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.57 |
| ▸ | LNPEP | Q9UIQ6 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | PLEC | Q15149 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1205232 | 0.88 | LNPEP (0.57) | GAAMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1306650 | 0.88 | GAA (0.67) | GAAMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1543144 | 0.88 | GAA (0.71) | GAAMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL1307539 | 0.87 | GAA (0.66) | GAAMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2245361 | 0.87 | GAA (0.66) | GAAMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2249029 | 0.87 | PTGER4 (0.80) | GAAMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29825520 | 0.87 | PTGER4 (0.80) | GAAMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13076223 | 0.86 | PTGER4 (0.56) | GAAMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL20797770 | 0.86 | PTGER4 (0.70) | GAAMAPTALDH1A1KDM4EHSD17B10 | |
| SCHEMBL22118804 | 0.84 | GAA (0.58) | GAAMAPTALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |