Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4830154 | 0.85 | PRKCA (0.51) | OGFRL1NR1I2PRKCAMMP12 | |
| SCHEMBL14253427 | 0.82 | NR1I2 (0.46) | OGFRL1NR1I2PRKCAMMP12KCNH2 | |
| SCHEMBL3937533 | 0.72 | PRKCA (0.47) | OGFRL1NR1I2PRKCAMMP12 | |
| SCHEMBL3944738 | 0.71 | NR1I2 (0.43) | OGFRL1NR1I2PRKCAMMP12 | |
| SCHEMBL4825585 | 0.70 | PRKCA (0.50) | NR1I2PRKCAMMP12 | |
| SCHEMBL13936853 | 0.70 | NR1I2 (0.50) | NR1I2PRKCAMMP12CNR1CNR2 | |
| SCHEMBL14253779 | 0.70 | PRKCA (0.50) | NR1I2PRKCAMMP12 | |
| SCHEMBL13940155 | 0.69 | PRKCA (0.48) | NR1I2PRKCAMMP12CNR1CNR2 | |
| SCHEMBL4020494 | 0.69 | PRKCA (0.48) | NR1I2PRKCAMMP12CNR1CNR2 | |
| SCHEMBL13940189 | 0.69 | PRKCA (0.48) | NR1I2PRKCAMMP12CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092000-A1 | INHIBITORS OF HCV REPLICATION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |