Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | AKT1 | P31749 | 5/20 | 0.51 |
| ▸ | AKT2 | P31751 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5333366 | 0.91 | POLB (0.49) | CNR1AKT1AKT2GRIA1GABRA2 | |
| SCHEMBL5351210 | 0.89 | CNR1 (0.54) | CNR1AKT1AKT2HPGDNPC1 | |
| SCHEMBL5342230 | 0.88 | CNR1 (0.56) | CNR1AKT1AKT2HPGDNPC1 | |
| SCHEMBL5343284 | 0.84 | AKT1 (0.53) | AKT1AKT2NPC1RAB9A | |
| SCHEMBL5318498 | 0.81 | AKT1 (0.48) | CNR1AKT1AKT2GRIA1 | |
| SCHEMBL5335702 | 0.80 | POLB (0.51) | CNR1AKT1AKT2GRIA1GABRA2 | |
| SCHEMBL5337506 | 0.80 | PHGDH (0.51) | CNR1AKT1AKT2HPGDGRIA1 | |
| SCHEMBL5337926 | 0.79 | CNR1 (0.58) | CNR1AKT1AKT2HPGDPDE4A | |
| SCHEMBL5322233 | 0.79 | CNR1 (0.58) | CNR1AKT1AKT2HPGDPDE4A | |
| SCHEMBL5344445 | 0.77 | AKT1 (0.66) | AKT1AKT2GABRA2GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |