Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.58 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.55 |
| ▸ | PDE4A | P27815 | 2/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 4/20 | 0.47 |
| ▸ | AKT2 | P31751 | 4/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.46 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337926 | 1.00 | CNR1 (0.58) | CNR1GABRA2GABRB2PDE4APDE4B | |
| SCHEMBL5333907 | 0.92 | CNR1 (0.53) | CNR1GABRA2GABRB2HPGDF2RL1 | |
| SCHEMBL5341500 | 0.89 | KMT2A (0.60) | CNR1GABRA2GABRB2PDE4APDE4B | |
| SCHEMBL5342501 | 0.89 | CCNC (0.45) | CNR1GABRA2GABRB2HPGDAKT1 | |
| SCHEMBL5345220 | 0.89 | KDM4E (0.59) | CNR1HPGDSLC2A1KMT2A | |
| SCHEMBL5318714 | 0.89 | POLB (0.56) | CNR1GABRA2GABRB2HSD17B10HPGD | |
| SCHEMBL5341068 | 0.89 | SLC2A2 (0.52) | CNR1SLC2A1 | |
| SCHEMBL5347128 | 0.88 | L3MBTL3 (0.51) | CNR1GABRA2GABRB2MEN1KMT2A | |
| SCHEMBL15071127 | 0.87 | F2RL1 (0.62) | CNR1GABRA2GABRB2PDE4APDE4B | |
| SCHEMBL5339197 | 0.86 | CASP1 (0.49) | CNR1GABRA2GABRB2HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | claimed |
| WO-2007086080-A2 | NOVEL IMIDAZO[1,2-a]PYRIDINE CANNABINOID RECEPTOR LIGANDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |