Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1471145 | 0.89 | SMN1; SMN2 (0.48) | KDM4EABL1LMNASCN9ASMN1; SMN2 | |
| SCHEMBL24963024 | 0.83 | SCN9A (0.42) | SCN9AHTT | |
| SCHEMBL1472680 | 0.83 | KDM4E (0.49) | KDM4EABL1LMNASMN1; SMN2HPGD | |
| SCHEMBL1470405 | 0.83 | KDM4E (0.49) | KDM4EABL1LMNASMN1; SMN2HPGD | |
| SCHEMBL1470403 | 0.83 | KDM4E (0.49) | KDM4EABL1LMNASMN1; SMN2HPGD | |
| SCHEMBL16196909 | 0.82 | KDM4E (0.48) | KDM4EABL1LMNASCN9ASMN1; SMN2 | |
| SCHEMBL27734364 | 0.81 | KDM4E (0.54) | KDM4EABL1LMNASMN1; SMN2HPGD | |
| SCHEMBL27734362 | 0.81 | KDM4E (0.54) | KDM4EABL1LMNASMN1; SMN2HPGD | |
| SCHEMBL17035908 | 0.79 | ADRB1 (0.60) | KDM4EABL1LMNASMN1; SMN2HPGD | |
| SCHEMBL231823 | 0.79 | ADRB1 (0.60) | KDM4EABL1LMNASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007076318-A2 | CAMPHOR-DERIVED CXCR3 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |
| WO-2007076318-A2 | CAMPHOR-DERIVED CXCR3 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-05 | — | — | WO | disclosed |