Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 17/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4104776 | 1.00 | P2RY12 (0.54) | P2RY12KDM4EHSD17B10GAAL3MBTL1 | |
| SCHEMBL4104756 | 0.82 | P2RY12 (0.64) | P2RY12KDM4EHSD17B10GAAL3MBTL1 | |
| SCHEMBL3221673 | 0.77 | P2RY12 (0.69) | P2RY12KDM4EHSD17B10CYP3A4CYP2C9 | |
| SCHEMBL5592396 | 0.77 | ALDH1A1 (0.55) | P2RY12KDM4EHSD17B10GAAL3MBTL1 | |
| SCHEMBL4112754 | 0.77 | P2RY12 (0.60) | P2RY12KDM4EHSD17B10GAAL3MBTL1 | |
| SCHEMBL4112758 | 0.77 | P2RY12 (0.60) | P2RY12KDM4EHSD17B10GAAL3MBTL1 | |
| SCHEMBL4115539 | 0.77 | P2RY12 (0.64) | P2RY12KDM4EHSD17B10GAAL3MBTL1 | |
| SCHEMBL4872969 | 0.76 | P2RY12 (0.61) | P2RY12KDM4EHSD17B10CYP3A4CYP2C9 | |
| SCHEMBL4872874 | 0.75 | KDM4E (0.53) | P2RY12KDM4EHSD17B10GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4104473 | 0.75 | P2RY12 (0.61) | P2RY12KDM4EHSD17B10CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836189-A1 | NOVEL PYRIDINE COMPOUNDS | AstraZeneca AB (SE) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006073361-A1 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2006-07-13 | — | — | WO | disclosed |