SCHEMBL531829

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2119988	0.91	TP53 (0.54)	PARP1MEN1KMT2ATP53KDM4E
	SCHEMBL532558	0.87	PARP1 (0.56)	PARP1MEN1KMT2AKDM4EALDH1A1
	SCHEMBL532840	0.84	PARP1 (0.56)	PARP1HSD17B10ALOX15USP2GAA
	SCHEMBL532670	0.84	HSD17B10 (0.57)	PARP1KMT2AALDH1A1POLBSMN1; SMN2
	SCHEMBL2121266	0.82	PARP1 (0.48)	PARP1MEN1KMT2ASMN1; SMN2HSD17B10
	SCHEMBL10222476	0.81	PARP1 (0.53)	PARP1ALDH1A1HSD17B10ALOX15USP2
	SCHEMBL531857	0.80	PARP1 (0.63)	PARP1MEN1KMT2AKDM4EHSD17B10
	SCHEMBL532477	0.79	PARP1 (1.00)	PARP1TP53POLBSMN1; SMN2HSD17B10
	SCHEMBL531865	0.78	PARP1 (0.48)	PARP1KDM4EALDH1A1SMN1; SMN2HSD17B10
	SCHEMBL531626	0.77	PARP1 (0.53)	PARP1KMT2ATP53HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.