SCHEMBL531865

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10222476	0.89	PARP1 (0.53)	PARP1HSD17B10ALOX15USP2GAA
	SCHEMBL532840	0.85	PARP1 (0.56)	PARP1HSD17B10ALOX15USP2GAA
	SCHEMBL2123411	0.82	PARP1 (0.52)	PARP1USP2GAASMYD3PDE3B
	SCHEMBL2119917	0.81	PARP1 (0.48)	PARP1HSD17B10ALOX15SMYD3ALDH1A1
	SCHEMBL531431	0.78	PARP1 (0.68)	PARP1HSD17B10ALOX15USP2SMYD3
	SCHEMBL532063	0.78	PARP1 (0.53)	PARP1HSD17B10SMYD3ALDH1A1SMN1; SMN2
	SCHEMBL532558	0.78	PARP1 (0.56)	PARP1HSD17B10ALOX15SMYD3KDM4E
	SCHEMBL532821	0.78	PARP1 (0.52)	PARP1HSD17B10ALOX15PDE3BPDE3A
	SCHEMBL531829	0.78	PARP1 (0.64)	PARP1HSD17B10ALOX15USP2GAA
	SCHEMBL532437	0.78	PARP1 (0.54)	PARP1HSD17B10ALOX15SMYD3PDE3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.