Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.48 |
| ▸ | EGFR | P00533 | 6/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 6/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | ACP1 | P24666 | 1/20 | 0.45 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.45 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.45 |
| ▸ | SSU72 | Q9NP77 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5318361 | 0.99 | TRPM8 (0.51) | TRPM8ROCK1EGFRERBB2PPARA | |
| SCHEMBL5321993 | 0.88 | TRPM8 (0.67) | TRPM8ROCK1NPC1RAB9ATSHR | |
| Hydrochloric Acid SCHEMBL5315581 | 0.87 | TRPM8 (0.66) | TRPM8ROCK1NPC1RAB9ATSHR | |
| SCHEMBL5122198 | 0.86 | HPGD (0.54) | TRPM8ROCK1PPARANPC1RAB9A | |
| SCHEMBL5120927 | 0.85 | TRPM8 (0.47) | TRPM8PPARANPC1RAB9AMEN1 | |
| SCHEMBL14464542 | 0.85 | TRPM8 (0.71) | TRPM8PPARAACP1PTPN12PTPN13 | |
| Hydrochloric Acid SCHEMBL5338163 | 0.84 | TRPM8 (0.70) | TRPM8PPARAACP1PTPN12PTPN13 | |
| SCHEMBL14464513 | 0.83 | TRPM8 (0.61) | TRPM8ROCK1RAB9APTPN12TSHR | |
| SCHEMBL14464074 | 0.83 | TRPM8 (0.60) | TRPM8NPC1RAB9ATSHRMEN1 | |
| SCHEMBL14463942 | 0.81 | TRPM8 (0.73) | TRPM8NPC1RAB9ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007080109-A1 | SUBSTITUDED BENZYLOXY-PHENYLMETHYLUREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |
| WO-2007080109-A1 | SUBSTITUDED BENZYLOXY-PHENYLMETHYLUREA DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2007-07-19 | — | — | WO | disclosed |