Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR6 | P46095 | 18/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL941030 | 0.87 | SLC6A2 (0.58) | HTR1ASLC6A2SLC6A3HRH1 | |
| Trifluoroacetic Acid SCHEMBL23830477 | 0.86 | GPR6 (0.47) | GPR6HTR1ASLC6A2SLC6A3 | |
| Hydrochloric Acid SCHEMBL2778482 | 0.86 | SLC6A2 (0.56) | HTR1ASLC6A2SLC6A3HRH1 | |
| Trifluoroacetic Acid SCHEMBL2253892 | 0.83 | KDM1A (0.41) | GPR6HTR1ASLC6A2SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL69823 | 0.77 | HRH1 (0.51) | HTR1ASLC6A2SLC6A3HRH1 | |
| Trifluoroacetic Acid SCHEMBL69693 | 0.77 | HRH1 (0.51) | HTR1ASLC6A2SLC6A3HRH1 | |
| SCHEMBL3126596 | 0.77 | HTR2C (0.48) | HTR1ASLC6A2SLC6A3HRH1 | |
| SCHEMBL5318471 | 0.76 | GPR6 (0.50) | GPR6 | |
| Trifluoroacetic Acid SCHEMBL15565383 | 0.76 | NPC1 (0.44) | GPR6 | |
| SCHEMBL31071547 | 0.76 | HTR2C (0.49) | HTR1ASLC6A2SLC6A3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007082079-A2 | PIPERIDINE AMIDE DERIVATIVES AS PROTEIN KINASE INHIBITORS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2007-07-19 | — | — | WO | disclosed |