Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 8/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.48 |
| ▸ | BCHE | P06276 | 4/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 6/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5969950 | 0.80 | SLC6A2 (0.59) | SLC6A2SLC6A3SLC6A4KDM1AMAOB | |
| SCHEMBL27922848 | 0.78 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4POLB | |
| SCHEMBL2583594 | 0.75 | BCHE (0.39) | SLC6A2SLC6A3SLC6A4BCHEACHE | |
| SCHEMBL12159639 | 0.75 | BCHE (0.39) | SLC6A2SLC6A3SLC6A4BCHEACHE | |
| SCHEMBL30259179 | 0.72 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4KDM1AMAOB | |
| SCHEMBL17729387 | 0.72 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4KDM1AMAOB | |
| SCHEMBL11203577 | 0.72 | IDO1 (0.51) | — | |
| SCHEMBL9036022 | 0.71 | EPHX2 (0.40) | BCHEACHEALDH1A1GAAPGR | |
| SCHEMBL20678609 | 0.70 | BCHE (0.40) | SLC6A2SLC6A3SLC6A4BCHEKDM1A | |
| SCHEMBL20678737 | 0.70 | BCHE (0.40) | SLC6A2SLC6A3SLC6A4BCHEKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007100583-A2 | PROPARGYLATED AMINOINDANS, PROCESSES FOR PREPARATION, AND USES THEREOF | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 2007-09-07 | — | — | WO | claimed |