Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 7/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | KDM1A | O60341 | 4/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.33 |
| ▸ | HTR3B | O95264 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.33 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4607072 | 0.87 | SLC6A2 (0.40) | SLC6A2SLC6A3SLC6A4HTR3EHTR3B | |
| SCHEMBL27922848 | 0.80 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4MAPTPOLB | |
| SCHEMBL5318520 | 0.80 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4KDM1AMAOB | |
| SCHEMBL30259179 | 0.73 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4KDM1AMAOB | |
| SCHEMBL17729387 | 0.73 | SLC6A2 (0.61) | SLC6A2SLC6A3SLC6A4KDM1AMAOB | |
| SCHEMBL5970111 | 0.72 | SLC6A2 (0.46) | SLC6A2SLC6A3SLC6A4KDM1AMAOB | |
| SCHEMBL5969949 | 0.72 | SLC6A2 (0.46) | SLC6A2SLC6A3SLC6A4KDM1AMAOB | |
| SCHEMBL2470428 | 0.72 | SLC6A2 (0.46) | SLC6A2SLC6A3SLC6A4KDM1AMAOB | |
| SCHEMBL30291012 | 0.71 | ALDH1A1 (0.34) | SLC6A2SLC6A3SLC6A4CHRNA7POLB | |
| SCHEMBL3201048 | 0.71 | SLC6A2 (0.56) | SLC6A2SLC6A3SLC6A4KDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738149-B1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMA (IL) | 2006-11-29 | — | — | EP | claimed |