SCHEMBL5318577

SCHEMBL5318577

C[C@@](CCN)(Oc1cccc2ccccc12)c1cccs1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 14/20 0.46
SLC6A2 P23975 12/20 0.46
SLC6A3 Q01959 11/20 0.46
HTR1B P28222 4/20 0.46
KDM4E B2RXH2 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HSD17B10 Q99714 1/20 0.42
HRH1 P35367 2/20 0.41
CYP1A2 P05177 2/20 0.41
CYP3A4 P08684 2/20 0.41
CYP2C19 P33261 2/20 0.41
MLNR O43193 1/20 0.41
CACNA1F O60840 1/20 0.41
ADRB1 P08588 1/20 0.41
HTR1A P08908 1/20 0.41
GAA P10253 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
DRD2 P14416 1/20 0.41
KCNE1 P15382 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1535358 1.00 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3HTR1BKDM4E
Hydrochloric Acid SCHEMBL4053969 0.99 SLC6A4 (0.45) SLC6A4SLC6A2SLC6A3HTR1BKDM4E
SCHEMBL2062229 0.88 SLC6A4 (0.50) SLC6A4SLC6A2SLC6A3HTR1BHRH1
SCHEMBL2062227 0.88 SLC6A4 (0.50) SLC6A4SLC6A2SLC6A3HTR1BHRH1
SCHEMBL11948165 0.87 KDM4E (0.45) SLC6A4SLC6A2SLC6A3HTR1BKDM4E
SCHEMBL11948170 0.87 KDM4E (0.45) SLC6A4SLC6A2SLC6A3HTR1BKDM4E
Hydrochloric Acid SCHEMBL15400700 0.86 SLC6A4 (0.49) SLC6A4SLC6A2SLC6A3HTR1BHRH1
Hydrochloric Acid SCHEMBL15400702 0.86 SLC6A4 (0.49) SLC6A4SLC6A2SLC6A3HTR1BHRH1
SCHEMBL11949108 0.85 KDM4E (0.44) SLC6A4SLC6A2SLC6A3HTR1BKDM4E
SCHEMBL11948172 0.85 KDM4E (0.44) SLC6A4SLC6A2SLC6A3HTR1BKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1587802-B1 PRODUCTION AND USE OF 3-METHYLAMINO-1-(2-THIENYL)-1-PROPANONE BASF AG (DE) 2007-11-14 EP disclosed
EP-1587802-A1 3-METHYLAMINO-1-(2-THIENYL)-1-PROPANONE, PRODUCTION AND USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 2005-10-26 EP disclosed
WO-2004065376-A1 3-METHYLAMINO-1-(2-THIENYL)-1-PROPANONE, PRODUCTION AND USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 2004-08-05 WO disclosed