Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 13/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | MLNR | O43193 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.50 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR2C | P28335 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2062229 | 1.00 | SLC6A4 (0.50) | SLC6A4SLC6A2SLC6A3HRH1MLNR | |
| Hydrochloric Acid SCHEMBL15400702 | 0.99 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HRH1MLNR | |
| Hydrochloric Acid SCHEMBL15400700 | 0.99 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3HRH1MLNR | |
| Oxalic Acid SCHEMBL2697141 | 0.93 | ALDH1A1 (0.46) | SLC6A4SLC6A2SLC6A3HRH1MLNR | |
| Oxalic Acid SCHEMBL2697146 | 0.93 | ALDH1A1 (0.46) | SLC6A4SLC6A2SLC6A3HRH1MLNR | |
| SCHEMBL1535358 | 0.88 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3HRH1MLNR | |
| SCHEMBL5318577 | 0.88 | SLC6A4 (0.46) | SLC6A4SLC6A2SLC6A3HRH1MLNR | |
| Hydrochloric Acid SCHEMBL4053969 | 0.86 | SLC6A4 (0.45) | SLC6A4SLC6A2SLC6A3HRH1MLNR | |
| SCHEMBL4438949 | 0.85 | KDM4E (0.39) | SLC6A4SLC6A2SLC6A3HRH1MLNR | |
| SCHEMBL11948170 | 0.85 | KDM4E (0.45) | SLC6A4SLC6A2SLC6A3HRH1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8614336-B2 | Process for preparing N-methyl-N-hydroxyl-3-(1-naphthyloxy)-3-(2-thienyl)propylamine derivative | SCI PHARMTECH, INC. (TW) | 2013-12-24 | — | — | US | disclosed |
| US-8148549-B2 | Preparation of (S)-(+)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl) propylamine using optically active methylhydroxylaminopropanol compound as an intermediate | SCI PHARMTECH, INC. (TW) | 2012-04-03 | — | — | US | disclosed |
| US-8148549-B2 | Preparation of (S)-(+)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl) propylamine using optically active methylhydroxylaminopropanol compound as an intermediate | SCI PHARMTECH, INC. (TW) | 2012-04-03 | — | — | US | disclosed |
| US-20100234619-A1 | PREPARATION OF (S)-(+)-N-METHYL-3-(1-NAPHTHYLOXY)-3-(2-THIENYL) PROPYLAMINE USING OPTICALLY ACTIVE METHYLHYDROXYLAMINOPROPANOL DERIVATIVE AS AN INTERMEDIATE | SCI PHARMTECH, INC. (TW) | 2010-09-16 | — | — | US | disclosed |
| US-20100234620-A1 | PROCESS FOR PREPARING N-METHYL-N-HYDROXYL-3-(1-NAPHTHYLOXY)-3-(2-THIENYL)PROPYLAMINE DERIVATIVE | SCI PHARMTECH, INC. (TW) | 2010-09-16 | — | — | US | disclosed |
| US-20100234620-A1 | PROCESS FOR PREPARING N-METHYL-N-HYDROXYL-3-(1-NAPHTHYLOXY)-3-(2-THIENYL)PROPYLAMINE DERIVATIVE | SCI PHARMTECH, INC. (TW) | 2010-09-16 | — | — | US | disclosed |
| US-20100234619-A1 | PREPARATION OF (S)-(+)-N-METHYL-3-(1-NAPHTHYLOXY)-3-(2-THIENYL) PROPYLAMINE USING OPTICALLY ACTIVE METHYLHYDROXYLAMINOPROPANOL DERIVATIVE AS AN INTERMEDIATE | SCI PHARMTECH, INC. (TW) | 2010-09-16 | — | — | US | disclosed |
| EP-2228372-A1 | Process for Preparing (S)-(+)-N-Methyl-3-(1-Naphthyloxy)-3-(2-Thienyl-Propylamine by using Optically Active Methylhydroxylaminopropanol Compound as an Intermediate | SCI Pharmatech, Inc. (TW) | 2010-09-15 | — | — | EP | disclosed |
| EP-2228372-A1 | Process for Preparing (S)-(+)-N-Methyl-3-(1-Naphthyloxy)-3-(2-Thienyl-Propylamine by using Optically Active Methylhydroxylaminopropanol Compound as an Intermediate | SCI Pharmatech, Inc. (TW) | 2010-09-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234620-A1 | PROCESS FOR PREPARING N-METHYL-N-HYDROXYL-3-(1-NAPHTHYLOXY)-3-(2-THIENYL)PROPYLAMINE DERIVATIVE | PNMT, NNMT, HNMT | SLC6A4 107/4885SLC6A2 106/4885SLC6A3 69/4885 |
| US-20100234619-A1 | PREPARATION OF (S)-(+)-N-METHYL-3-(1-NAPHTHYLOXY)-3-(2-THIENYL) PROPYLAMINE USING OPTICALLY ACTIVE METHYLHYDROXYLAMINOPROPANOL DERIVATIVE AS AN INTERMEDIATE | PNMT, HNMT, BHMT2 | SLC6A4 276/4885SLC6A2 207/4885SLC6A3 196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.