Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | DRD5 | P21918 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 8/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327803 | 0.98 | DRD2 (0.52) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL29795153 | 0.89 | DRD2 (0.61) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL5327927 | 0.84 | DRD2 (0.49) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL30364101 | 0.79 | CHRNA7 (0.46) | CHRNA7 | |
| SCHEMBL3866433 | 0.79 | CHRNA7 (0.46) | CHRNA7 | |
| SCHEMBL3863017 | 0.79 | CHRNA7 (0.46) | CHRNA7 | |
| SCHEMBL26180067 | 0.77 | DRD2 (0.45) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL21142551 | 0.76 | CHRNA7 (0.74) | CHRNA7SIGMAR1 | |
| SCHEMBL3402404 | 0.76 | CHRNA7 (0.74) | CHRNA7SIGMAR1 | |
| SCHEMBL24570645 | 0.75 | CHRNA7 (0.40) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1622923-A4 | MOLECULAR DETECTION SYSTEMS UTILIZING REITERATIVE OLIGONUCLEOTIDE SYNTHESIS | RIBOMED BIOTECHNOLOGIES INC (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2007099423-A1 | 1-PYRROLIDINE INDANE DERIVATIVES AS HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| WO-2007099423-A1 | 1-PYRROLIDINE INDANE DERIVATIVES AS HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2007-09-07 | — | — | WO | disclosed |
| EP-1622923-A2 | MOLECULAR DETECTION SYSTEMS UTILIZING REITERATIVE OLIGONUCLEOTIDE SYNTHESIS | Ribomed Biotechnologies, Inc. (US) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004096997-A2 | MOLECULAR DETECTION SYSTEMS UTILIZING REITERATIVE OLIGONUCLEOTIDE SYNTHESIS | RIBOMED BIOTECHNOLOGIES, INC. (US) | 2004-11-11 | — | — | WO | disclosed |