Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 2/20 | 1.00 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | ACACA | Q13085 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.51 |
| ▸ | DHFR | P00374 | 1/20 | 0.50 |
| ▸ | FYN | P06241 | 2/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045347 | 0.77 | TLR8 (1.00) | MEN1KMT2ATLR8NPC1RAB9A | |
| SCHEMBL7694555 | 0.77 | MEN1 (0.62) | MEN1KMT2ATLR8NPC1RAB9A | |
| SCHEMBL1767756 | 0.76 | MEN1 (1.00) | MEN1KMT2ATLR8NPC1RAB9A | |
| SCHEMBL8574353 | 0.76 | KMT2A (0.74) | MEN1KMT2ATLR8NPC1RAB9A | |
| SCHEMBL21223576 | 0.75 | MEN1 (0.60) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL9146072 | 0.75 | MEN1 (0.60) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL30702310 | 0.74 | KDM4E (1.00) | MEN1KMT2ATLR8NPC1RAB9A | |
| SCHEMBL23496978 | 0.73 | MEN1 (0.66) | MEN1KMT2ATLR8NPC1RAB9A | |
| SCHEMBL22509831 | 0.73 | KMT2A (0.71) | MEN1KMT2ATLR8NPC1RAB9A | |
| SCHEMBL30452106 | 0.73 | KDM4E (0.57) | MEN1KMT2ANPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007078034-A1 | A COMPOSITION FOR INHIBITING THE C-KIT PORTEIN CONTAINING BENZIMIDAZOLE AMINE DERIVATIVES OR AMINOQUINOLINE DERIVATIVES | AMOREPACIFIC CORPORATION (KR) | 2007-07-12 | — | — | WO | claimed |
| WO-2007078034-A1 | A COMPOSITION FOR INHIBITING THE C-KIT PORTEIN CONTAINING BENZIMIDAZOLE AMINE DERIVATIVES OR AMINOQUINOLINE DERIVATIVES | AMOREPACIFIC CORPORATION (KR) | 2007-07-12 | — | — | WO | disclosed |