Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | GUCY1A1 | Q02108 | 4/20 | 0.37 |
| ▸ | GUCY1B1 | Q02153 | 4/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318952 | 1.00 | ENPP2 (0.43) | ENPP2PTGDR2CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL1049586 | 0.92 | ENPP2 (0.46) | ENPP2PTGDR2CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL1049585 | 0.92 | ENPP2 (0.46) | ENPP2PTGDR2CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL5321447 | 0.90 | ENPP2 (0.48) | ENPP2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5269926 | 0.90 | ENPP2 (0.46) | ENPP2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5321449 | 0.90 | ENPP2 (0.48) | ENPP2CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5321725 | 0.88 | ENPP2 (0.38) | ENPP2PTGDR2CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL5321729 | 0.88 | ENPP2 (0.38) | ENPP2PTGDR2CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL1050476 | 0.88 | ENPP2 (0.52) | ENPP2PTGDR2CYP1A2CYP3A4CYP2C8 | |
| SCHEMBL1047075 | 0.88 | PTGDR2 (0.43) | ENPP2PTGDR2CYP1A2CYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | claimed |