SCHEMBL5319040

SCHEMBL5319040

CNC(=O)Oc1ccc2c(c1)C(NF)CC2

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ACHE P22303 19/20 0.57
MAOA P21397 2/20 0.47
MAOB P27338 2/20 0.47
BCHE P06276 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5321946 0.87 ACHE (0.57) ACHEMAOAMAOBBCHE
Hydrochloric Acid SCHEMBL5319086 0.86 ACHE (0.59) ACHE
SCHEMBL13389456 0.82 ACHE (0.56) ACHEBCHE
SCHEMBL13389296 0.82 ACHE (0.56) ACHEBCHE
SCHEMBL5271924 0.82 ACHE (0.56) ACHE
SCHEMBL3301612 0.82 ACHE (0.52) ACHEMAOAMAOBBCHE
SCHEMBL3300157 0.82 ACHE (0.78) ACHEMAOAMAOBBCHE
SCHEMBL3298737 0.82 ACHE (0.78) ACHEMAOAMAOBBCHE
SCHEMBL3301607 0.82 ACHE (0.52) ACHEMAOAMAOBBCHE
SCHEMBL3295837 0.81 ACHE (0.73) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007100583-A2 PROPARGYLATED AMINOINDANS, PROCESSES FOR PREPARATION, AND USES THEREOF TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 2007-09-07 WO disclosed