Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 17/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318430 | 0.93 | ITK (0.49) | ITKHRH3CNR2 | |
| SCHEMBL5318236 | 0.88 | ITK (0.49) | ITKHRH3CNR2 | |
| SCHEMBL5316323 | 0.86 | ITK (0.48) | ITKHRH3CNR2 | |
| SCHEMBL5320026 | 0.82 | PTGER4 (0.47) | KDM2B | |
| Water SCHEMBL5319087 | 0.81 | PTGER4 (0.46) | KDM2B | |
| SCHEMBL5318415 | 0.80 | KDM4E (0.49) | CNR2KDM2B | |
| SCHEMBL5315353 | 0.80 | HRH3 (0.42) | ITKHRH3 | |
| SCHEMBL5318297 | 0.78 | CNR2 (0.51) | ITKCNR2 | |
| SCHEMBL5317398 | 0.78 | ITK (0.49) | ITKCNR2 | |
| SCHEMBL5315592 | 0.76 | ITK (0.53) | ITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | claimed |
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |