Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITK | Q08881 | 16/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5317398 | 0.91 | ITK (0.49) | ITKCNR2NPC1RAB9A | |
| SCHEMBL5319079 | 0.88 | ITK (0.49) | ITKCNR2HRH3 | |
| SCHEMBL5316323 | 0.87 | ITK (0.48) | ITKCNR2HRH3 | |
| SCHEMBL5318216 | 0.83 | ITK (0.43) | ITKCNR2BCHEOPRM1 | |
| SCHEMBL5318430 | 0.80 | ITK (0.49) | ITKCNR2HRH3 | |
| SCHEMBL5318297 | 0.79 | CNR2 (0.51) | ITKCNR2 | |
| SCHEMBL5315733 | 0.78 | PTGER4 (0.51) | — | |
| SCHEMBL5319931 | 0.77 | HRH3 (0.49) | CNR2HRH3 | |
| SCHEMBL5315592 | 0.77 | ITK (0.53) | ITK | |
| SCHEMBL5375164 | 0.75 | KDM4E (0.54) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | claimed |
| WO-2007069053-A1 | BENZIMIDAZOLE ANTAGONISTS OF THE H-3 RECEPTOR | PFIZER PRODUCTS INC. (US) | 2007-06-21 | — | — | WO | disclosed |