Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | CCR2 | P41597 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157011 | 1.00 | MAPK1 (0.36) | MAPK1NPSR1MEN1GAAKMT2A | |
| SCHEMBL14449048 | 0.87 | HCRTR1 (0.32) | — | |
| SCHEMBL756177 | 0.87 | HCRTR1 (0.32) | — | |
| SCHEMBL4087184 | 0.87 | HCRTR1 (0.32) | — | |
| SCHEMBL13697137 | 0.87 | HCRTR1 (0.32) | — | |
| SCHEMBL13696843 | 0.77 | MMP9 (0.32) | — | |
| SCHEMBL13696839 | 0.77 | MMP9 (0.32) | — | |
| SCHEMBL13696841 | 0.77 | MMP9 (0.32) | — | |
| SCHEMBL5315532 | 0.75 | MMP9 (0.31) | — | |
| SCHEMBL28442215 | 0.74 | HCRTR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007092705-A2 | PROCESS FOR PREPARING GEMCITABINE AND ASSOCIATED INTERMEDIATES | CHEMAGIS LTD. (IL) | 2007-08-16 | — | — | WO | disclosed |