Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574806 | 0.88 | PTGES (0.85) | PTGESALDH1A1TSHRKMT2AHPGD | |
| SCHEMBL4924661 | 0.88 | PTGES (0.67) | PTGESALDH1A1TSHRKMT2AHPGD | |
| SCHEMBL3001458 | 0.85 | PTGES (0.51) | PTGESALDH1A1TSHRKMT2AHPGD | |
| SCHEMBL4918706 | 0.84 | PTGES (0.64) | PTGESALDH1A1TSHRKMT2AHPGD | |
| SCHEMBL3579996 | 0.83 | PTGES (0.78) | PTGESALDH1A1TSHRKMT2AHPGD | |
| SCHEMBL3574862 | 0.82 | PTGES (0.77) | PTGESALDH1A1TSHRKMT2AHPGD | |
| SCHEMBL4914078 | 0.82 | PTGES (0.61) | PTGESALDH1A1TSHRKMT2AHPGD | |
| SCHEMBL4914068 | 0.82 | PTGES (0.60) | PTGESALDH1A1TSHRKMT2AHPGD | |
| SCHEMBL3573824 | 0.82 | PTGES (0.72) | PTGESALDH1A1TSHRKMT2AHPGD | |
| SCHEMBL4923416 | 0.82 | PTGES (0.60) | PTGESALDH1A1TSHRKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844013-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006077364-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2006-07-27 | — | — | WO | disclosed |