Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5319914 | 1.00 | NR1H2 (0.39) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL5318957 | 0.94 | NR1H2 (0.41) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL5318955 | 0.94 | NR1H2 (0.41) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL5318211 | 0.91 | ENPP2 (0.40) | NR1H2NR1H3ENPP2PPARGLMNA | |
| SCHEMBL5318209 | 0.91 | ENPP2 (0.40) | NR1H2NR1H3ENPP2PPARGLMNA | |
| SCHEMBL5316757 | 0.90 | KCNK3 (0.37) | NR1H2NR1H3RXRAENPP2SLC22A12 | |
| SCHEMBL5316760 | 0.90 | KCNK3 (0.37) | NR1H2NR1H3RXRAENPP2SLC22A12 | |
| SCHEMBL5320419 | 0.90 | NR1H2 (0.42) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL5320416 | 0.90 | NR1H2 (0.42) | NR1H2NR1H3NR1I2NR3C1AR | |
| SCHEMBL5317765 | 0.87 | NR1H2 (0.40) | NR1H2NR1H3ENPP2GRM2SLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786424-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | The University of Kansas (US) | 2007-05-23 | — | — | EP | claimed |
| WO-2006023704-A2 | LONIDAMINE ANALOGUES AND THEIR USE IN MALE CONTRACEPTION AND CANCER TREATMENT | UNIVERSITY OF KANSAS (US) | 2006-03-02 | — | — | WO | claimed |