Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | GCLC | P48506 | 1/20 | 0.32 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.32 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.32 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755924 | 0.87 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL1168875 | 0.87 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL7420375 | 0.87 | SLC7A5 (0.50) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL28319951 | 0.85 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL28319949 | 0.85 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL3673862 | 0.81 | USP2 (0.45) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL598942 | 0.81 | USP2 (0.45) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL587730 | 0.81 | USP2 (0.45) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL6739408 | 0.81 | USP2 (0.45) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 | |
| SCHEMBL19981311 | 0.81 | USP2 (0.45) | SLC7A5SLC1A3SLC1A2SLC1A1LAP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102617364-B | Hydroxymethyl diamine compound and preparation method and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2014-04-23 | — | — | CN | disclosed |
| CN-102617364-A | Hydroxymethyl diamine compound and preparation method and application thereof | NANJING UNIVERSITY OF TECHNOLOGY | 2012-08-01 | — | — | CN | disclosed |
| US-20070258899-A1 | Diagnostic and therapeutic agents | KARYON-CTT LTD (FI) | 2007-11-08 | — | — | US | disclosed |
| WO-2007113385-A1 | DIAGNOSTIC AND THERAPEUTIC AGENTS | KARYON-CTT LTD (FI) | 2007-10-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070258899-A1 | Diagnostic and therapeutic agents | YBX1, MLX, TPX2 | SLC7A5 3712/4885SLC1A3 4472/4885SLC1A2 4787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.