Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | CBS | P35520 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320009 | 1.00 | CNR1 (0.54) | CNR1CNR2PTGS2EPHX2FAAH | |
| SCHEMBL5273078 | 0.90 | CNR1 (0.64) | CNR1CNR2PTGS2EPHX2FAAH | |
| SCHEMBL5273071 | 0.90 | CNR1 (0.64) | CNR1CNR2PTGS2EPHX2FAAH | |
| SCHEMBL31040565 | 0.90 | CNR1 (0.64) | CNR1CNR2PTGS2EPHX2FAAH | |
| SCHEMBL31040560 | 0.90 | CNR1 (0.64) | CNR1CNR2PTGS2EPHX2FAAH | |
| SCHEMBL13206731 | 0.85 | PPARA (0.58) | CNR1EPHX2FAAHPPARA | |
| SCHEMBL26430149 | 0.81 | PPARA (0.48) | CNR1CNR2PPARACBSHIF1A | |
| SCHEMBL31185832 | 0.79 | PTGS2 (0.73) | CNR1CNR2PTGS2 | |
| SCHEMBL18586439 | 0.79 | PTGS2 (0.73) | CNR1CNR2PTGS2 | |
| SCHEMBL31185803 | 0.79 | PTGS2 (0.73) | CNR1CNR2PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005122670-A2 | BIOMONITORED SYNTHESIS ROUTE FOR LARGE SCALE PREPARATION OF CARDOL (BILOBOL) AND 11Δ-CARDOL | KARDOL INDÚSTRIA QUÍMICA LTDA. (BR) | 2005-12-29 | — | — | WO | claimed |
| WO-2005122670-A3 | BIOMONITORED SYNTHESIS ROUTE FOR LARGE SCALE PREPARATION OF CARDOL (BILOBOL) AND 11Δ-CARDOL | KARDOL IND QUIMICA LTDA (BR) | 2007-07-05 | — | — | WO | disclosed |
| WO-2005122670-A2 | BIOMONITORED SYNTHESIS ROUTE FOR LARGE SCALE PREPARATION OF CARDOL (BILOBOL) AND 11Δ-CARDOL | KARDOL INDÚSTRIA QUÍMICA LTDA. (BR) | 2005-12-29 | — | — | WO | disclosed |