Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | TACR1 | P25103 | 2/20 | 0.58 |
| ▸ | PTPRA | P18433 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18000223 | 0.84 | MAPT (0.64) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL18274732 | 0.84 | MAPT (0.67) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL18274731 | 0.84 | MAPT (0.67) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL5925171 | 0.84 | MAPT (0.67) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL5925173 | 0.84 | MAPT (0.67) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL10586676 | 0.83 | TACR1 (0.66) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL27568427 | 0.83 | TACR1 (0.66) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL23723484 | 0.82 | MAPT (0.76) | MAPTLMNAKDM4EMEN1KMT2A | |
| SCHEMBL29472033 | 0.82 | MAPT (0.76) | MAPTLMNAKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL10587119 | 0.82 | TACR1 (0.65) | MAPTLMNAKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075931-A2 | REACTIVE HETEROCYCLIC DERIVATIVES AND METHODS FOR THEIR SYNTHESIS AND USE | BIOSITE INCORPORATED (US) | 2007-07-05 | — | — | WO | disclosed |