Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.60 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | CLK2 | P49760 | 1/20 | 0.60 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16011743 | 0.80 | KDM4E (0.42) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL5725016 | 0.79 | KCNH2 (0.56) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL5725012 | 0.79 | KCNH2 (0.56) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL16011744 | 0.79 | KCNH2 (0.55) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL5790693 | 0.79 | KDM4E (0.78) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL13841370 | 0.79 | KDM4E (0.67) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL15132795 | 0.78 | KDM4E (0.85) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL16009404 | 0.77 | KDM4E (0.82) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL14578644 | 0.77 | KCNH2 (0.60) | KDM4EKCNH2HPGDALDH1A1HSD17B10 | |
| SCHEMBL13973963 | 0.76 | KCNH2 (0.71) | KDM4EKCNH2HPGDALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007099431-A2 | AN AQUEOUS LIQUID PHARMACEUTICAL COMPOSITIONS OF GATIFLOXACIN | WOCKHARDT LTD (IN) | 2007-09-07 | — | — | WO | disclosed |
| WO-2006004561-A1 | PROCESS FOR THE PREPARATION OF GATIFLOXACIN AND REGENERATION OF DEGRADATION PRODUCTS | KRKA, TOVARNA ZDRAVIL, D.D., NOVO MESTO (SI) | 2006-01-12 | — | — | WO | disclosed |