Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 6/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | ALPI | P09923 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | XIAP | P98170 | 1/20 | 0.56 |
| ▸ | TPH1 | P17752 | 9/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | GRB2 | P62993 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.49 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5313209 | 0.98 | SLC7A5 (0.56) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL539325 | 0.90 | SRR (0.54) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL539324 | 0.90 | SRR (0.54) | SLC7A5PTGS1ALPIPKMXIAP | |
| SCHEMBL7451018 | 0.90 | SRR (0.54) | SLC7A5PTGS1ALPIPKMXIAP | |
| Hydrochloric Acid SCHEMBL3999043 | 0.89 | SRR (0.55) | SLC7A5PTGS1ALPIPKMXIAP | |
| Hydrochloric Acid SCHEMBL1151366 | 0.89 | SRR (0.55) | SLC7A5PTGS1ALPIPKMXIAP | |
| Hydrochloric Acid SCHEMBL7451013 | 0.89 | SRR (0.55) | SLC7A5PTGS1ALPIPKMXIAP | |
| Hydrochloric Acid SCHEMBL1151363 | 0.89 | SRR (0.55) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine Methyl Ester SCHEMBL29087575 | 0.89 | SLC7A5 (0.73) | SLC7A5PTGS1ALPIPKMXIAP | |
| Phenylalanine Methyl Ester SCHEMBL5693500 | 0.89 | SLC7A5 (0.73) | SLC7A5PTGS1ALPIPKMXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185204-A1 | Crystalline forms of 3-biphenyl-4-yl-(2S)-[(4'-trifluoromethyl-biphenyl-4-carbonyl)-amino]-propionic acid, and methods of use | TRANSTECH PHARMA, INC. | 2007-08-09 | — | — | US | disclosed |
| WO-2007087148-A1 | CRYSTALLINE FORMS OF 3-BIPHENYL-4-YL-(2S)-[(4'-TRIFLUOROMETHYL-BIPHENYL-4-CARBONYL)-AMINO]-PROPIONIC ACID, AND METHODS OF USE | TRANSTECH PHARMA, INC. (US) | 2007-08-02 | — | — | WO | disclosed |